Elderly patients with obstructive sleep apnea syndrome in patients with intermittent hypoxia.docVIP

 PAGE \* MERGEFORMAT 6 Elderly patients with obstructive sleep apnea syndrome in patients with intermittent hypoxia [Keywords:] Aged; obstructive sleep apnea syndrome; intermittent hypoxia Intermittent hypoxia is obstructive sleep apnea syndrome (OSAS) in the typical pathophysiological processes that lead to high blood oxygen saturation is low, stimulation of peripheral chemoreceptors causes sympathetic activation 1, making the risk of cardiovascular disease significantly 2 increase. elderly are at high risk of cardiovascular disease, so the article tries hypoxemia in elderly patients with OSAS and non-elderly patients differ from the perspective of understanding of sleep-disordered breathing elderly people at high risk of cardiovascular disease factors. 1 Subjects and methods 1.1 The subjects were 135 patients from July 2005 to June 2008 at the Huashan Hospital Sleep Health Center received polysomnography (PSG) examination and diagnosis of OSAS patients. Asked about the history, excluding chronic obstructive pulmonary disease, asthma, lung cancer, interstitial lung disease, pulmonary embolism, hyperthyroidism, hypothyroidism, acromegaly, acute and chronic liver and kidney dysfunction, cancer and other diseases .135 elderly patients were divided into the age group of 64 patients ( 70.5 + -9.9) years old, female 6 and 71 cases of non-elderly group, age (41.7 + -10.5) years and female 6, according to severity into 2 subgroups mild: 5 / h hypopnea index (AHI) lt;20 / h, moderate and severe: AHIgt; = 20 / h. 1.2 Methods PSG (TEDA Emerging Technology Co., Ltd., RS 9601-type) monitor, subjects sleep the night 21:00 into the monitoring room for more than 7 h sleep monitoring, monitoring of projects, including EEG, EOG, nose and mouth flow, thoracoabdominal movements, ECG, blood oxygen saturation, the next day for manual analysis of the various indicators. 1.3 Statistical analysis of all experimental data using SPSS11.0 package deal, normal distribut