Elderly people with atrial fibrillation taking amiodarone-induced hypothyroidism clinical analysis.docVIP

 PAGE \* MERGEFORMAT 7 Elderly people with atrial fibrillation taking amiodarone-induced hypothyroidism clinical analysis Authors: CHEN Yan-mei, Wu Yuntao, Bing-kuen [Keywords:] Atrial fibrillation; elderly; amiodarone; hypothyroidism Atrial fibrillation (AF) with drug therapy is the main treatment in most patients [1]. Multi-old atrial fibrillation with heart failure or heart failure, commonly used as a switch to resume amiodarone atrial fibrillation and maintaining sinus rhythm drugs, the resulting increase in reports of various adverse reactions. I Section 7 cases treated in the past one year due to taking amiodarone-induced thyroid dysfunction in patients, are reported as follows. A clinical data I Section 7 cases treated in the past one year due to taking amiodarone-induced thyroid dysfunction in patients, 6 were male and 1 female, aged 65 to 87 years, with an average 78.4 years of age. All were taking amiodarone for paroxysmal atrial fibrillation or sinus rhythm maintenance treatment, in which 3 patients with primary hypertension, history of hypertension 4 to 15 years with coronary heart disease, old myocardial infarction in 3 cases The combined heart failure, aneurysm in 2 cases, sick sinus syndrome to install a permanent cardiac pacemaker in 2 cases, renal dysfunction and decompensation in 1 case. Of which 6 patients were transferred after the resumption of sinus rhythm maintenance dose of amiodarone to take a week 0.7 ~ 1.4 g, the medication 13 ~ 58 months after the occurrence of thyroid function is low, an average of 25.6 months. 1 cases due to onset of paroxysmal atrial flutter given after taking amiodarone loading 0.2 g 1 time / d maintenance dose of two months, that is found in hypothyroidism. 7 patients had no symptoms of thyroid dysfunction, because thyroid function taking amiodarone routine check found that in order to serum thyroid-stimulating hormone (TSH) increased first main 5.76 ~ 68.52 mIU / L (reference value of 0.35 ~ 5.5 mIU / L