Elderly type 2 diabetes the pathophysiology of renal damage.docVIP

 PAGE \* MERGEFORMAT 10 Elderly type 2 diabetes the pathophysiology of renal damage [Abstract] in elderly patients with type 2 diabetes, renal damage in the pathological diagnosis and clinical manifestations. Methods 116 cases of kidney damage associated with type 2 diabetes mellitus elderly patients kidney biopsy, analysis of its pathology and laboratory indexes . Results of 116 cases aged patients with type 2 diabetes diagnosed by renal biopsy pathology, of which 69 patients with diabetic kidney disease (DKD), accounting for 59.5%; 47 cases diagnosed as non-diabetic kidney disease (NDRD), accounting for 40.5 %. DKD Group diagnostic accuracy rate of 59.4%, NDRD group 31.9% diagnostic accuracy. two BUN, Scr, is associated with diabetic retinopathy and hematuria was significantly (P lt;0.05), age, blood pressure, fasting blood glucose, glycated hemoglobin, lipids, and 24 h urinary protein were not significantly different (Pgt; 0.05). Conclusion elderly type 2 diabetic patients with a considerable portion of the kidney damage NDRD, specific lesions on kidney biopsy has important clinical significance. [Keywords:] 2 diabetes mellitus; diabetic nephropathy; non-diabetic renal diseases Diabetic kidney disease (diabetic kidney disease, DKD) clinical practice guidelines in 2007 for the first time been proposed to replace the previous diabetic nephropathy (DN) concept. DKD as the most common of diabetes, irreversible microvascular complications, is the final One of the important causes of end stage renal disease (1,2). and DKD patients receiving biopsies from 10% to 25% of the non-diabetic kidney disease (non-diabetic renal disease, NDRD), the nature of the NDRD and DKD, treatment and prognosis were significantly different (3), therefore, how to identify clinical patients with diabetic kidney damage is NDRD or DKD, to guide clinical treatment is extremely important. At present, the domestic on the elderly type 2 diabetic patients with pathological study of ren