Electron microscopy of thyroid hormone on rat pituitary - ovarian axis of the role of the.docVIP

 PAGE \* MERGEFORMAT 8 Electron microscopy of thyroid hormone on rat pituitary - ovarian axis of the role of the Author: Li Wei Fan Ying Yuan-kang Liu Bai Tao Liu invention [Abstract] Objective: To observe the thyroid hormone (thyroxine, T 4) on rat pituitary, ovary, ultrastructure. Methods: Transmission electron microscopy after thyroxine 0.6 μ g * g-1 * d-1, ig, 21d rat pituitary, ovary, ultrastructure changes. Results: The nuclear membrane of rat pituitary gonadotropin cells is not clear, some of the nuclear membrane disappears, the mitochondria or disappearance of spinal fracture, there medullary changes and vacuolation; rough endoplasmic reticulum are swollen, there part of the phenomenon of degranulation . Ovarian endocrine cells in experimental rats, some of the gaps between cells, granule cells, mitochondria appear myeloid transformation and vacuolation, Golgi apparatus, ribosomes reduced, showing that myeloid body. Conclusion: Long-term high-dose application of thyroid hormone in rats pituitary, ovary, ultrastructure of endocrine cells produce degenerative changes. [Keywords:] Thyroxine; pituitary; ovary; ultrastructure Thyroid hormone is to maintain the body’s normal metabolism of important hormones necessary for it is also the clinical treatment of certain diseases commonly used drugs. Clinical research data shows that thyroid hormone on the pituitary - ovarian axis also contributed. Recent studies have shown that: Thyroid hormone and ovarian function in a relationship may exist between. Mammalian sinus vitro studies have shown that pre-follicular thyroid hormone on in vitro cultured oocytes produce harmful effects, markedly inhibited the formation of oocytes Douqiang [1]. The thyroid hormone on the pituitary - ovarian axis systematic study of endocrine function, very little coverage at home and abroad. This study, systematic observation of the thyroid hormone on rat pituitary - ovarian axis ultrastructure of secretory cells, designed to pr