Elimination of toxic granule liver in rats with hepatic encephalopathy electroencephalogram.docVIP

 PAGE \* MERGEFORMAT 7 Elimination of toxic granule liver in rats with hepatic encephalopathy electroencephalogram Of: Yan Wei Yang Yujie Liu Tiejun Zhang Jingzhou Keywords: hepatic drug elimination Granule; hepatic encephalopathy; EEG Hepatic encephalopathy is a serious liver disease caused by metabolic disorders as the foundation, change of consciousness and coma as the main manifestation of the central nervous system dysfunction syndrome 1, mainly cause of the current treatment and symptomatic therapy. Studies show that drug consumption is increasing liver granule decoction liquid derived from hepatic encephalopathy for the empirical treatment of liver and kidney organs, yin fluid and Xiere catharsis, with bowel toxicity, lowering blood ammonia, diarrhea stool, reduce intestinal endotoxin absorption, protect the liver brain, the role of prevention and treatment of hepatic encephalopathy. Consumption of liver toxicity observed in this study Granule hepatic encephalopathy of different doses on EEG in rats, and to explore its mechanism of hepatic encephalopathy. 1 Materials and methods 1.1 Animals 110 Wistar rats, male, weighing 240 ~ 260 g, license number SCXK (Kyrgyzstan) 2003 007. The adaptability of feeding 1w, were randomly divided into control group (A, 10), model group (B group, 20), lactitol group (C group, 20), drugs, high consumption of liver Granule (D group , 20), medium (E group, 20 rats) and low (F group, 20 rats) groups. 1.2 drugs, reagents and equipment Thioacetamide (AR, Shanghai Chemical Reagent Company product, batch number 920903); 20% urethane (distilled water); drug elimination by the liver Granule Scrophulariaceae, Ophiopogon, habitat, rhubarb, composed of Glauber’s salt, the water Fried, ethanol and other technology into granules; lactitol (JCTT Pharmaceutical Co., Ltd.). EEG machine for NIHON KOHDEN MAF 5 type l6 lead EEG machine (Japan). 1.3 Methods 1.3.1 Model Preparation In addition to the norm