Electrical stimulation of the saphenous nerve on the spinal cord cfos gene expression.docVIP

 PAGE \* MERGEFORMAT 11 Electrical stimulation of the saphenous nerve on the spinal cord cfos gene expression Of: Yang Yu, Yang Jingyu, Guo, Shang Li Wang 3, Chenkui Min, Wu Minfan, Han Qing [Abstract] Objective: To investigate whether somatic noxious stimulation caused by spinal cord neurons of c fos gene expression changes. Methods: Immunohistochemical methods using somatic nociceptive stimulation at different times after the saphenous nerve, spinal cord neurons of c fos gene expression. Results: noxious electrical stimulation of the saphenous nerve can cause spinal cord Fos protein expression was significantly increased; noxious electrical stimulation of the saphenous nerve after 30min significantly increased, 60min to increase the most obvious, 120min after beginning to fade. Conclusion: studies have shown that electrical stimulation of saphenous nerve injury can cause spinal cord Fos protein expression increased significantly, this expression was time dependent. [Keywords:] c fos gene; spinal cord; saphenous nerve; physical pain; Immunohistochemistry Effect of Electrically Stimulating Saphenous Nerve on c fos Gene Expression in Spinal Cord Neurons of Rats YANG Yu1, YANG Jing yu1, GUO Li2, SHANG Li hong3, CHEN Kui min3, WU Min fan4 *, HAN Qing5 (1.Life Science and Bio pharmaceutical College, Shenyang Pharmaceutical University, Shenyang 110015, China; 2.Scientific Experimental Center of Shenyang Medical College; 3.Functional Experimental Center of Shenyang Medical College; 4.Department of Physiology, Shenyang Medical College; 5 . Depart of Hygiene, PLA 95979 Army) AbstractObjective: To observe the expression changes of the c fos gene in spinal cord neurons by somatic noxious stimulation.Methods: The electrical stimulation of saphenous nerve at different times was studied, the changes of spinal cord neurons c fos gene expression were observed by immunohistochemical technique . Results: Spinal cord Fos protein expression could lead to a si