Elderly patients with impaired glucose tolerance metformin metabolic syndrome and its effects on serum C reactive protein in clinical observation.docVIP

 PAGE \* MERGEFORMAT 9 Elderly patients with impaired glucose tolerance metformin metabolic syndrome and its effects on serum C reactive protein in clinical observation Study: WANG Hai-ying Wang Lifang Hu Haifeng Wang Lanjun [Keywords:] metformin, metabolic syndrome, C-reactive protein Metabolic syndrome (MS is associated with insulin resistance (IR) of a group of metabolic abnormalities, including central obesity, high blood sugar, blood pressure, abnormal lipid metabolism, MS is the composition independent cardiovascular disease risk factors, these factors interact, increasing the relative risk of cardiovascular disease (1). impaired glucose tolerance (IGT) is the evolution from normal glucose tolerance into type 2 diabetes (T2DM in the intermediate stage, IGT in patients with MS more often accompanied by constituent. In order to prevent and delay the elderly T2DM and cardiovascular disease, this paper, metformin plus lifestyle intervention and way of life in elderly patients with IGT combined treatment of MS, compare the efficacy observed for elderly patients with IGT combined treatment of MS basis. 1 Subjects and methods 1.1 Object As from January 2005 to February 2007 IGT in our hospital 50 cases of elderly patients with combined MS, 27 males and 23 females, aged 60 to 76 (mean (68.4 + -7.6 years), IGT diagnostic criteria consistent with 1998 the provisions of WHO (2). MS in April 2004 by the Chinese Medical Association Diabetes diagnostic criteria will be made (3), exclude serious heart, liver, kidney disease, acute and chronic infectious diseases, cancer and so on. were not taking antihypertensive drugs, lipid-lowering drugs and non-steroidal drugs. healthy control group for the same period 40 cases, 22 males and 18 females, aged 60 to 76 (mean (69.1 + -8.9 years), two groups of age, no significant difference in gender composition. 1.2 Methods IGT patients were randomly divided into combined MS lifestyle intervention group and lif