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Fatty liver disease research progress and ultrasonic diagnosis
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Fatty liver disease research progress and ultrasonic diagnosis
[Keywords:] Progress in ultrasound diagnosis fatty liver disease
Fatty liver disease (Fatty Liver Disease, FLD) refers to the liver due to various causes excessive accumulation of fat, accumulation of hepatic lobule lesions to diffuse macrovesicular fatty liver cells into pathological features of the clinical syndrome [1] . For some reason causing the liver fatty acid uptake, synthesis, operation and utilization of loss of balance, resulting in the gradual accumulation of liver lipid, and more than 5% of liver wet weight; or histologically more than 50% have fatty liver of this clinical phenomenon is known as the FLD. If the total weight of the liver lipids of liver wet weight and 10% to 24%, that is, moderate FLD; accounted for 25% of liver wet weight and more than 50%, that is, severe FLD. clinical patients may be asymptomatic or only mild liver Fullness feeling; severe feeling of nausea in patients with liver swelling or pain, fatigue, weakness, indigestion, and the emergence of liver enlargement, abdominal full, abnormal liver function.
1 FLD classification
FLD clinically divided into two categories, namely, alcoholic fatty liver disease (Clinical Aspects of fatty liver Disease, ALD) and non-alcoholic fatty liver disease (Non-Alcoholic Fatty Liver Disease, NAFLD) [2]. ALD drinking by the transition caused by ethanol and its metabolite acetaldehyde directly cause alcoholic liver toxicity is the basic cause of liver damage. The cause of NAFLD is a lot, some diseases such as diabetes, hyperlipidemia, obesity, taking drugs on liver damage and toxins (such as phosphorus, carbon tetrachloride, etc.) can lead to NAFLD [3]. NAFLD sub-two categories of primary and secondary, the former with insulin resistance and genetic susceptibility, the latter by some special reasons. overnutrition and overweight due to excessive weight gain, diabetes, hyperlipidemia and other meta
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