Flurbiprofen ester used in patients with gynecologic laparoscopic surgery clinical study of preemptive analgesia.docVIP

 PAGE \* MERGEFORMAT 3 Flurbiprofen ester used in patients with gynecologic laparoscopic surgery clinical study of preemptive analgesia [Keywords:] flurbiprofen ester laparoscopic pain Flurbiprofen ester trade names Kay Fun is the use of Lipo-that is, drug targeting technology to produce a can with a targeted analgesic effect of intravenous injection of non-steroidal anti-inflammatory drugs in foreign countries as a single postoperative analgesia and the treatment of cancer pain [1], while the domestic clinical application is not common. Authors from January 2006 to December 2007 to be administered at different times by observing the flurbiprofen ester on gynecological laparoscopic postoperative pain, and to explore its preemptive analgesia efficacy and safety. Report are as follows. A clinical data 1.1 General Information Select ASA Ⅰ ~ Ⅱ grade elective gynecological laparoscopy line (including the removal of uterine fibroids, ovarian cysts out) in 90 patients, aged 26 to 65 years of age; weight of 44 ~ 62kg. Were randomly divided into A, B groups, A group, preoperative treatment group, B group after treatment group, all patients have a coagulation function were normal, there was no history of chronic pain and long-term history of taking analgesics. The stability of conventional oral premedication 5mg and intramuscular atropine 0.5mg. 1.2 Anesthesia and monitoring All patients were using intravenous endotracheal intubation inhalation anesthesia. Inducing medication for midazolam 0.04mg/kg, propofol 1.5mg/kg, fentanyl 4μ g/kg, atracurium 1mg/kg, anesthesia maintained at 2% ~ 4% sevoflurane inhalation and 4 ~ 6mg / (kg * h) of propofol micro-pump injection, intermittent recovery el qa Atracurium. Two groups of patients with routine monitoring of blood pressure (BP), heart rate (HR), electrocardiogram (ECG), blood oxygen saturation (SpO2) and end-tidal carbon dioxide (PetCO2), record of blood loss. Methods of analgesia and observation of targets A group