Fujie Experimental Study of Antibacterial Effect of particle.docVIP

 PAGE \* MERGEFORMAT 9 Fujie Experimental Study of Antibacterial Effect of particle Author: Lin-xia Li Jie, XU Shu-lan Wang Peng Xiu-Qin Zhang [Abstract] Objective To study the observation of women cleaning particles in vitro and in vivo antibacterial activity. Methods Plate double dilution of the women’s clean particles against clinical isolates of 64 common clinical Gram-positive and gram-negative bacteria in vitro antibacterial activity. Chosen Staphylococcus aureus, Escherichia coli, Proteus, and beta-hemolytic streptococcus was the protection of bacterial infection in mice experiments. The results of the drug in vitro against Staphylococcus aureus, Staphylococcus epidermidis and Escherichia coli The role of the strongest, MIC50, respectively 0.25,2 and 1 g * L-1; in vivo experiments also showed that Staphylococcus aureus, Escherichia coli and deformation the body caused by bacteria infected animals have better protection. Conclusion against clinical Gram-positive and gram-negative bacteria all have a strong killing or inhibition. [Keywords:] housewife cleaning particles; antibacterial; Escherichia coli; Staphylococcus aureus Abstract: ObjectiveTo evaluate the antibacterial activities of Fujie granule in vitro and in vivo. MethodsMinimal inhibitory concentrations (MIC) of Fujie granule was determined using two-fold broth dilution method against 64 strains of common G + and G-bacteria isolated from hospital. The protective effects on mice infected by taphylococcus aureus, staphylococcus epidermidis, proteus species and streptococcus pyogens were also tested.ResultsFor staphylococcus aureus, staphylococcus epidermidis, Escherichia coli, Fujie granule exhibited the strongest inhibitory effects, the MIC was 0.25,2 and 1g / L, respectively. The in vivo test indicated that Fujie granule had protective effects on mice infected by taphylococcus aureus, staphylococcus epidermidis, proteus species and streptococcus pyogens.ConclusionFujie granule has strong inhi