Genetic and environmental factors on the twin sisters sex hormones affect the.docVIP

 PAGE \* MERGEFORMAT 6 Genetic and environmental factors on the twin sisters sex hormones affect the [Keywords:] female; pairs of twins; heritability; adolescence Abstract: Objective To explore female puberty before and after the serum estradiol (E2) and testosterone (T) of the change trend to evaluate the relative effects of genetic and environmental factors. School-based registration method to raise 6 to 18 year-old female twins 180 pairs, including monozygotic twins (MZ) 132 pairs of dizygotic twins (DZ) 48 pairs, according to Tanner stages of puberty standards, measured by radioimmunoassay fasting serum estradiol (E2) and testosterone (T) concentrations. The results of serum E2 and T concentrations increased with the process of puberty, Tanner Ⅳ reach a peak, Tanner Ⅴ period declined slightly; genetic effects analysis showed that serum E2 and T twins even within the mean difference, even within the variance MZDZ; of the phenotypic variance attributable to the portion of the additive genetic factors were 40% (E2), and 47% (T); stages heritability estimates show E2 and T were better than had cramps set of genetic group and the breasts are not developing the next wave of groups . Conclusion adolescent females serum E2 and T also affected by genetic and environmental factors, menstrual cramps after the significant role of genetic factors. Keywords:: women; pairs of twins; heritability; adolescence Influence of genetic and environmental factors on serum estradiol and testosterone of twin girls Abstract: Objective To explore the change of serum estradiol (E2) and testosterone (T) concentrations throughout the puberty of girls and estimate the effects of genetic and environmental factors on serum E2 and T concentrations.Methods The study population consisted of 180 pairs of twin girls aged 6 to 18 of whom.132 pairs monozygotic twins (MZ) and 48 pairs dizygotic twins (DZ), who were all from Qingdao city of Shandong province.Anthropometric measurement and pub