Hyperlipidemia and vascular endothelial cell function assay Progress Indicators.docVIP

 PAGE \* MERGEFORMAT 11 Hyperlipidemia and vascular endothelial cell function assay Progress Indicators [Keywords:] hyperlipidemia assay of vascular endothelial cell function index Hyperlipidemia (Hypolipidemic) is the serum total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) is too high or serum high density lipoprotein (HDL) too low a systemic metabolic disorders, is now a serious hazard to human health diseases. As in recent years on vascular endothelial cells (VEC) deepening understanding of the biological function of hyperlipidemia on the pathogenesis of immune and biochemical indicators in addition, the focus has gradually shifted VEC dysfunction. This paper intends to hyperlipidemia and vascular endothelial cell function assay indices are reviewed. 1, blood lipid Hyperlipidemia is frequently detected in lipid levels TC, LDL-C, HDL-C, TG. In recent years, serum apolipoprotein (Apo) and lipoprotein (Lpc (a)) has become a testing target. Is generally considered that many identified risk factors, elevated serum cholesterol level was the only other risk factors not sufficient to induce and promote the coordination and atherosclerosis (AS factor in the development of [1]. LDL through cross into the vascular endothelial cell barrier function after direct effect of nitric oxide, inhibition of endothelium-dependent vasodilation. LDL modified by oxidation easily expressed by macrophages scavenger receptor recognition, and thus the formation of foam cells by their phagocytic large number of foam cells that form the skin, including the first aggregation The AS disease - lipid stripes. lipid deposition may interfere with the skin, including endothelial cells (EC synthesis and release of endothelium-derived vasoactive factors NO and PGI2, the imbalance of coagulation and fibrinolytic systems, resulting in thrombosis. HDL Damage is considered to be a protective factor against AS, through participation in TC reverse transport, and promot