Irbesartan dose captopril treatment of chronic congestive heart failure clinical observation.docVIP

 PAGE \* MERGEFORMAT 8 Irbesartan dose captopril treatment of chronic congestive heart failure clinical observation [Abstract] Objective To observe the high-dose captopril (Capoten United Irbesartan treatment of chronic congestive heart failure clinical efficacy. Methods 139 patients with selected chronic congestive heart failure were randomly divided into two separate high-dose captopril treatment group (n = 61) and in the irbesartan tablets 150mg / day and gradually increase the amount on the basis of captopril tablets to the maximum tolerated dose group (n = 78). observed the two groups after 8 months in the cardiothoracic ratio, left ventricular end diastolic diameter, left ventricular end systolic diameter, left ventricular ejection fraction (LVEF, functional class, 6 minute walk test, hospitalization, mortality and other projects. The results of Section 8 months ???reduction in the number of hospitalization significant effect (P lt;0.01,6-minute walking distance, left ventricular end-diastolic and end-systolic diameter, LVEF, etc. captopril group than the single superior (P lt;0.05, in the cardiothoracic ratio, cardiac function, no significant difference in mortality. Conclusion Irbesartan compared with captopril captopril alone the treatment of chronic congestive heart failure have superior clinical efficacy and is worthy of promotion. [Keywords:] irbesartan congestive heart failure 1 Materials and Methods 1.1 General Information Select July 2004 -2009 139 cases in October in our hospital with chronic congestive heart failure (CHF patients, 81 patients were male, female 58 cases. Aged 27-78 years, mean age 57.2 years, the wind Cor two narrow two closed 11 cases, 52 cases of coronary heart disease, cardiomyopathy 33 cases, 43 patients with high heart disease. cardiac function (NYHA grade 31 grade , grade 69, grade 39. acute myocardial infarction during the observation period, acute myocarditis, the limitations of cardiomyopathy, hypertr