Irinotecan combined with capecitabine in the treatment of metastatic colorectal cancer observation and nursing care.docVIP

 PAGE \* MERGEFORMAT 10 Irinotecan combined with capecitabine in the treatment of metastatic colorectal cancer observation and nursing care 【Abstract】 Objective To investigate the irinotecan combined with capecitabine in the treatment of advanced colorectal cancer the efficacy and care. Methods 20 patients with advanced colorectal cancer patients receiving oral capecitabine 1250mg / (m2.d), 2 times / day, and continued for 14 days; CPT-11 180mg/m2, intravenous infusion, 90 minutes, the first day, every 3 Zhou repeated. Results 41 patients have completed treatment. Conclusion Careful observation and care is the foundation of the program to ensure the completion of chemotherapy. Keywords: Irinotecan Kang Kapei gemcitabine chemotherapy Care A clinical data 1.1 General Information October 2006 -2009 years, our department in hospital in January with pathologically confirmed metastasis and recurrence in advanced colorectal cancer in 41 cases, 35 males and 6 females; aged 30 -68 years of age; 18 cases of colon, rectum cancer, 23 cases of which 38 cases after surgery, KPSgt; 60 hours, blood, liver and kidney function, ECG normal, non-chemotherapy taboo sign. Each case were more than 4 courses of the whole group of patients four cycles of the 16 cases, 5 cycles of 5 cases, 6 cycles of 20 cases, a total of 203 cycles. 1.2 methods are used two kinds of drug combination chemotherapy, capecitabine orally 1250mg/m2.d, 2 times / day, orally half an hour after the meal, and even served 14 days; irinotecan 180mg/m2 of 5% glucose 500ml slow drip Note 90 minutes, the first day, repeated every 3 weeks. 1.3 Results The major toxic reactions were diarrhea, hand-foot syndrome, acetylcholine syndrome, neutropenia syndrome, gastrointestinal tract reaction. Through careful observation and care, reducing chemotherapy side effects, ensuring the smooth progress of chemotherapy. 2 Care 2.1 The psychological care for the patients