Irbesartan treatment of chronic heart failure bisoprolol combined clinical observation.docVIP

 PAGE \* MERGEFORMAT 12 Irbesartan treatment of chronic heart failure bisoprolol combined clinical observation Of: Kewei Liang, Li Shanghai, Ke Yiping [Abstract] Objective To observe the combined effects of irbesartan in chronic heart failure(CHF) in patients. Methods 98 patients with CHF were randomly divided into treatment group (50 cases) and control group (48 cases), general treatment control group the treatment group in the general treatment based on the use of bisoprolol 1.25 ~ 10 mg and irbesartan 75 ~ 150 mg, both day 1. bisoprolol started taking a dose of 1.25 mg, gradually increase the dose to the patients ability The maximum dose and can be long-term maintenance treatment to the end of the experiment, the initial dose of irbesartan 75 mg, followed up for 1 a. before and after treatment for 6 min walk test, respectively, and record the walking distance, as well as echocardiography left ventricular fractional shortening (LVFS) and left ventricular ejection fraction (LVEF). Results A total of 96 patients completed the study (treatment group and control group 48 cases). the treatment group during treatment readmission was 22.9% (11/48) , significantly lower than the control group 47.9% (23/48) (2 = 6.558, P lt;0.05), treatment of 1 a, the clinical efficacy of the treatment group than the control group, the difference was statistically significant (Hc = 5.050, P lt;0.05), and compared before treatment, the treatment group blood pressure, 6min walking distance, LVFS and LVEF improved significantly (P lt;0.01), while the control group before and after treatment to improve these indicators are not obvious. Conclusions ?CHF United irbesartan can improve the prognosis of patients. [Keywords:] -blockers, angiotensin receptor antagonist, heart function Chronic heart failure (CHF) as a common cardiovascular disease, is the old cause of death among cardiovascular diseases [1]. Studies have shown that, ACEI drugs can improve the prognosis of CHF