Isatis pharmacological research and clinical application of.docVIP

 PAGE \* MERGEFORMAT 17 Isatis pharmacological research and clinical application of Isatis (Isatis tinctoria L.) as a cruciferous plant, its roots and leaves can be used as medicine, medicine, said Banlangen dried roots, dry leaves medicine called Daqingye, Banlangen and Daqingye’s basically the same potency, there is Xiehuo , detoxification, cooling blood and other effects, mainly in the eastern provinces, Henan, Shanxi and other places [a]. Clinical case studies have shown that Isatis cure mumps, viral enteritis, genital warts, hepatitis B, influenza viruses, flat wart and other viral diseases [2]. There were also reports Isatis the adjustment of immune cells secrete IL-2, TNF-α and to enhance the role of cellular immune function [3], as well as anti-reactive oxygen species, anti-inflammatory and antibacterial effects [4,5]. Because of its wide range of applications, it has high research value. Is now on its chemical constituents and pharmacological effects, to make a brief overview. A chemical composition The main chemical constituents of Isatis are: alkaloids substances, such as indigo, indirubin, indigo glycoside, indigo red, adenosine, mustard glycosides, a new mustard glycosides, tryptamine ketone, 1 - thiocyanate -2 - hydroxy -3 - butene, black mustard glycosides, 4,3 (H) - quinazolinone. Steroid substances such as β -sitosterol, γ -sitosterol. A variety of amino acids such as arginine, proline, tyrosine, valine, γ -aminobutyric acid. In addition, reported in the literature pointed out that the quinazolinone also Isatis active ingredients [6]. 2 Pharmacology Isatis Qingrejiedu as a traditional Chinese medicine, pharmacological studies have found it, it has antibacterial, antiviral, antipyretic and anti-inflammatory, anti-tumor, enhance the immune system and other role, is a prospect with the development of Chinese medicine. 2.1 The antibacterial effect of water extract of Isatis Staphylococcus aureus, Staphylococcus epidermidis, B. subt