Intraperitoneal hyperthermic perfusion chemotherapy in the treatment of ovarian cancer care.docVIP

 PAGE \* MERGEFORMAT 9 Intraperitoneal hyperthermic perfusion chemotherapy in the treatment of ovarian cancer care Authors: Min, Shen-yu, ZHENG Ying, dry-Xia Keywords: intraperitoneal chemotherapy; ovarian cancer; Care Ovarian cancer is the female genital tract carcinoma in the highest mortality of a tumor, the early no obvious symptoms, most patients had had treatment with widespread metastatic intra-abdominal surgery has been impossible to root out. Ovarian cancer with abdominal pelvic spread, planting as the main transfer via. Cytoreductive surgery combined with chemotherapy, even patients with complete remission, there is still limited to 50% ~ 70% of abdominal pelvic recurrence and eventually leads to death. Intraperitoneal chemotherapy for a long time to make the abdominal cavity to maintain high drug concentrations, increasing drug and tumor extensive contacts. Hyperthermia can effectively increase the penetration of drugs on the tumor to increase the cytotoxic drugs, and improve advanced recurrent ovarian cancer efficacy [1  2]. I Bureau since August 2004 using central venous catheters in the abdominal cavity for peritoneal perfusion thermo-chemotherapy, and achieved satisfactory results, are reported as follows. 1 Data and methods 1.1 Clinical data 24 patients were married, aged 32 to 70 years old, all cases were confirmed by pathological diagnosis of ovarian cancer, of which 9 cases with ascites. All the cases were intra-abdominal indwelling central venous catheter, I intraperitoneal perfusion thermo-chemotherapy. 1.2 Methods Before the end of the closure of abdominal surgery, at a distance of 3 ~ 5 cm incision in the abdomen, replace single-chamber central venous catheter in the abdominal cavity, the depth of 18 ~ 20 cm, with the heparin cap closure catheter outside the mouth, closed abdominal suture will be later catheter fixed in the abdominal wall skin, and then 3 M transparent dressing cove