IVIG treatment of patients with recurrent abortion NK cells.docVIP

 PAGE \* MERGEFORMAT 15 IVIG treatment of patients with recurrent abortion NK cells Of: Liwei Ru Tan Jianping Chen Hui Liu Yukun Zhang Jianping Wang spent Wang Yunhui Zhang Rui Liu Yinglin [Abstract] [Objective] intravenous immunoglobulin (IVIG) therapy on patients with recurrent spontaneous abortion (RSA) in peripheral blood NK cells. [Method] The study group comprised 31 patients with RSA patients underwent intravenous immunoglobulin protein (IVIG) therapy in the treatment of patients detected by flow cytometry before and after the NK cells in peripheral blood NK cell cytotoxicity and the proportion of all lymphocytes; 26 cases of RSA patients did not receive IVIG control group, the first detection of NK cells detected toxicity and the proportion of NK cells after 10 days in the first review of these projects. [Results] Before treatment, NK cell toxicity study group (19.7 + - 8.7)%, NK cells was (21.4 + - 8.2)%, the experimental group after treatment NK cytotoxicity (13.1 + - 3.7)%, NK cell ratio (19.3 + - 7.5)%; the control group the first test, NK cytotoxicity was (20.1 + - 7.0)%, NK cells was (21.0 + - 8.1)%, retest interval of 10 d, NK cytotoxicity was (19.8 + - 7.2)%, NK cells was (21.2 + - 7.7)%. IVIG study group patients before and after treatment and proportion of peripheral blood NK cytotoxicity was significantly lower There were significant differences (P lt;0.05), while the control group before and after the twice the proportion of peripheral blood NK cell cytotoxicity and no significant difference (Pgt; 0.05); of patients before and after IVIG changes in peripheral blood NK cell cytotoxicity and NK cell percentage before and after IVIG no significant change in the correlation (Pgt; 0.05). [Conclusion] IVIG treatment on the proportion of NK cells have reduced toxicity and regulatory role. [Keywords:] recurrent abortion; intravenous immunoglobulin; NK cytotoxicity; NK cell ratio Abstract: [Objective] To discuss the influence of intraveno