Klebsiella pneumoniae producing ESBLs Surveillance of antimicrobial resistance.docVIP

 PAGE \* MERGEFORMAT 5 Klebsiella pneumoniae producing ESBLs Surveillance of antimicrobial resistance Keywords:: Heihe city; Klebsiella pneumoniae; drug resistance [Abstract] Objective To investigate the hospitals of Klebsiella pneumoniae (Kp) resistance of the status quo, in order to guide clinical rational use of antimicrobial agents provide a scientific basis. Methods disk diffusion method (KB method) on the Kp to 14 antimicrobial drug susceptibility testing, producing extended spectrum β -lactamases (ESBLs) of the screening by the United States Committee for Clinical Laboratory Standards (NCCLS) recommended paper confirmed Act. The results from 2003 to 2006 were isolated from clinical specimens Kp 97 strains in which ESBLs-positive 25. In addition to imipenem things right the other 13 have varying degrees of resistance to antibiotics and cephalosporins drug resistance is higher. Conclusion resistance of Heihe City, Kp is very serious, it is necessary Kp for dynamic monitoring of drug resistance to guide clinical practice. [Keywords:] Heihe city; Klebsiella pneumoniae; drug resistance In recent years, Klebsiella pneumoniae (Kp) has become a common opportunistic pathogen of nosocomial infection, often caused by respiratory infections. With the high-performance broad-spectrum antimicrobial agents widely used, Kp of certain strains of cephalosporin and quinolone acquired drug resistance. To understand the status of the city resistant Kp for clinical provide the basis for rational use of antimicrobial agents, we have isolated 97 Court Kp were determined. 1 Materials and methods 1.1 Sources of Klebsiella pneumoniae isolates from 97 hospital in February 2003 ~ April 2006 in-patient and outpatient sputum, throat swab, urine, pus and other specimens. Quality control strains Escherichia coli ATCC 25922, Klebsiella pneumoniae ATCC 700603, were purchased from the Ministry of Health clinical examination center. 1.2 Bacterial identification by ‘national clinical l