Lingzhi Capsule long-term toxicity of experimental study in rats.docVIP

 PAGE \* MERGEFORMAT 10 Lingzhi Capsule long-term toxicity of experimental study in rats [Abstract] Objective To observe the continuous fed rats given Lingzhi capsules produced toxicity. Method of Ganoderma lucidum capsules 1.87,0.94,0.47 g / kg continuous gavage 26 weeks, delivery end of the test body weight, urine, routine hematology, blood biochemistry, organ coefficient and histopathological changes. Results of each dose group rats developed normally, the test results no abnormal changes associated with drug use, the main organs does not appear toxic pathological lesions. Conclusion Ganoderma lucidum capsules fed long-term continuous no toxicity, long-term use safe. [Keywords:] Ganoderma lucidum capsules long-term toxicity in rats Abstract: ObjectiveTo observe the long term toxicity reaction of rats given Ganoderma lucidum capsule continuously.MethodsRats of three experimental groups were given Ganoderma lucidum capsule (ig) at doses of 1.87,0.94,0.47 g / kg * d-1 for twenty-six weeks . The avoirdupois, urine, hematology, blood biochemistry, and ratio of viscera to body were measured. The major organs were examined by the pathology.ResultsThe abnormity induced by Ganoderma lucidum capsule was not found in all results, and the pathological figures of major organs were normal.ConclusionThere is no toxicity of Ganoderma lucidum capsule given to rats for long term, indicating that it is safe to administrate Ganoderma lucidum capsule continuously. Keywords:: Ganoderma lucidum capsule; Long term toxicity; Rats Ganoderma lucidum is a kind of large-scale high-value medicinal fungi, containing essential amino acids, fatty acids, major and trace elements, vitamin C, E, carotene and biological activity of polysaccharides, are necessary for human health, good dietary fiber Source [1], immune regulation, anti-tumor, anti-cancer, liver protection and treatment of cardiovascular and cerebrovascular disease, lowering blood sugar, blood fat, removing free radicals and