Lipid Research Group and Its.docVIP

 PAGE \* MERGEFORMAT 27 Lipid Research Group and Its Of: Zhu Chao Wang Yiming Luo Guoan Hu Ping Liang Qionglin [Abstract] the diversity of biological functions of lipids and its metabolism and a variety of diseases and development are closely related. Lipids analysis to quantify the study of disease pathogenesis and diagnosis and treatment, and pharmaceutical R amp; D has a very important biological significance. the rapid development of technology, especially mass spectrometry and combined with the use of technology to promote continuous improvement of lipid analysis. fat group study of biological samples is the overall analysis of the lipid is an important metabolic component of genomics, can promote the metabolism of the development of proteomics. This article on biological functions of lipids, lipid analysis and lipid status of genomics research briefly reviewed. [Keywords:] fat group study, lipid analysis, electrospray ionization mass spectrometry, metabolomics, review 1 Introduction Lipids is the organism’s energy provider, involved in a number of life activities, has a very important physiological functions. Lipid molecules interact with other compounds to form a complex metabolic process, the occurrence of disease organisms, an important impact on development. It is reported that many diseases are associated with lipid metabolism disorder, such as: diabetes, obesity, Alzheimer’s disease, cancer, etc. [1 ~ 6]. Therefore, the living body and the metabolism of lipids of Pathogenesis and diagnosis of disease treatment, and the focus of pharmaceutical R amp; D process. To get a more comprehensive biological samples lipid information, to better reflect the role of lipids in vivo mechanism, and to find disease-related biomarkers or metabolism of, in order to provide the scientific basis for the treatment of diseases, scientists have done for lipid analysis of the overall focus of the study. With the development of analytical chemistry of life