Lithospermum efficacy of treating allergic purpura Experimental Analysis of the mechanism.docVIP

 PAGE \* MERGEFORMAT 12 Lithospermum efficacy of treating allergic purpura Experimental Analysis of the mechanism [Abstract] Objective Lithospermum treating allergic purpura mechanism. Methods reticuloendothelial system phagocytic function in mice experiments and observation of passive cutaneous anaphylaxis Lithospermum decoction on immune function of mice. Results (1 Lithospermum soup low, medium and high dose group phagocytic index and phagocytic coefficient K @ was significantly lower than the saline group, and showed dose-effect relationship, (2 Lithospermum soup can reduce the thymus index, and the high dose group compared with the saline group statistically significant (P lt;0.05; spleen index among the groups, but no statistical significance; (3 Lithospermum soup percentage inhibition of each treatment group was also higher than in the saline group, and showed dose-effect relationship, but no statistical significance. Conclusion Lithospermum soup may be a prescription to inhibit immune function, through the suppression of the immune, anti-allergic, anti-allergic used to treat allergic purpura. [Keywords:] Lithospermum Tom purpura effective mechanisms of allergic Study Henoch-Schonlein purpura (HSP is a common bleeding disorders in children, one of the overflow of blood in the skin, mucous membrane under, there petechia ecchymosis, the pressure of their clinical features do not fade, often accompanied by epistaxis, bleed at the nose gear, rather then hematemesis, hematochezia, hematuria. The disease belongs to Chinese medicine, “Blood”, the ancient Chinese recorded in the “Grape epidemic” “muscle bleed at the nose” “Purpura Wind” and other syndromes, there are similarities with the disease. HSP in recent years the incidence is rising, due to recurrent infections and other reasons easily understood, but most of good prognosis, because 45% to 65% of the patients complicated with renal involvement and affect the prognosis. The precise cause and pa