Mavericks vertebral osteoporosis model of rapid establishment.docVIP

 PAGE \* MERGEFORMAT 2 Mavericks vertebral osteoporosis model of rapid establishment Authors: Yang Binkui, Lei Wei, Wang Jun, Li Yun-ming [Abstract] Objective: Using disodium ethylene diamine tetra-acetic acid (EDTA  Na2) decalcification method for rapid establishment of bovine model of vertebral osteoporosis. Methods: The four fresh calf spine, each with 6 to 13 select the first vertebral body A total of 32 vertebrae, using randomized block design method is divided into Ⅰ ~ Ⅷ a total of eight area groups; using four kinds of treatment methods: A treatment group (EDTA  Na2 demineralized 3 wk), B treatment group (EDTA  Na2 decalcification 2 wk), C treatment group (without the use of EDTA  Na2 decalcification), D treatment group (EDTA  Na2 decalcification 4 wk). in each group were measured vertebral bone mineral density (BMD), the screw into the same size universal spine system (UPASS) pedicle screws, test the maximum axial pull-out strength (Fmax) and the energy absorption values, while each group is made to take a small amount of cancellous bone tissue biopsies. Results: A, B, D handle group BMD mean, Fmax, and the mean value of the mean energy absorption are lower than C treatment group (P