Medical scleral tissue adhesive bonding penetrating wounds in rabbit eyes and experimental study comparing traditional suture.doc

 PAGE \* MERGEFORMAT 15 Medical scleral tissue adhesive bonding penetrating wounds in rabbit eyes and experimental study comparing traditional suture Of: Wang Rui, Wu Nan, Wu Yan, Weng Chuanhuang, ZENG Yu Xiao, Huo Shu Jia, Wang [Abstract] Objective To investigate a octyl cyanoacrylate as the main medical chemistry scleral tissue adhesive in rabbit eyes closed the possibility of full-thickness tear. Methods 45 adult rabbits the Establishment of the scleral penetrating injury model, the right eye with a medical adhesive bonding, the left eye suture, 3,7,14,30,90 days after observation of the degradation of medical adhesive, compared to observe the healing of the wound tissue pathology. Results of medical glue scleral wound closed quickly. after each observation time point , eyes, posterior segment inflammation was not observed. electron microscopy and light microscopy tissue wounds healed. With the scleral wound healing, anti-ball pressure gradually increased. medical tissue adhesives chemical decomposition of absorption after 3 months. Conclusion Organization of Medical Chemistry adhesives can be effectively sealed scleral penetrating injury. [Keywords:] sclera; penetrating wounds; tissue adhesives; a octyl cyanoacrylate; suture; rabbit Abstract: Objective To investigate the feasibility of adhesion of chemical tissue adhesive (2 Octyl Cyanoacrylate) for sclerotic penetrating wound.Methods Forty five Japan rabbits were randomly divided into five groups, each group had nine rabbits.Right eyes were cyanoacrylate adhesive group, left eyes were suture group.On days 3,7,14,30 and 90 after surgery, the conditions of conjunctiva and anterior chamber were observed by Slit lamp biomicroscopy after surgery; the condition of sclerotic wound healing and cyanoacrylate adhesive degradation were observed; the tensile strength of eyeball was measured; the tissue of corneal wounds were observed by light microscope and transmission electron microscope examination.Resu