Metoprolol in acute myocardial infarction before and after intervention changes in QT dispersion.docVIP

 PAGE \* MERGEFORMAT 5 Metoprolol in acute myocardial infarction before and after intervention changes in QT dispersion [Keywords:] myocardial infarction, metoprolol divergence QT dispersion (QTd) as a simple, non-invasive reflection of ventricular repolarization heterogeneity method is widely taken seriously. In recent years, studies have shown that acute myocardial infarction (AMI) after prolonged QTd is a universal phenomenon, and with malignant closely related to the occurrence of arrhythmia. -blockers can reduce mortality in patients with AMI, myocardial ischemia may be related, but the impact on cardiac electrophysiology little studied. We observed QTd after AMI intervention metoprolol changes of -blockers when the impact of AMI. 1 Materials and Methods 6-24 of onset of AMI patients with small-time hospitalized and 61 cases (47 cases were male and 14 female) aged 38-70 years, mean 58.7 + -10.2 years old. All patients had no electrolyte imbalance, not taking antiarrhythmic drugs, no sinus bradycardia, degrees atrioventricular block and severe heart failure. randomly divided into two groups (31 cases) and control group (30 cases), the two asked the case of gender, age, infarct location, similar severity. the treatment of severe sinus bradycardia (“50 beats / min), degrees atrioventricular block, severe heart failure is eliminated. watchers given metoprolol 50-125mg / d oral, plus conventional anti-ischemic treatment for 4 weeks, control group received the same anti-ischemic treatment for 4 weeks. not given metoprolol. QTd measurements taken conventional 12-lead ECG (Nihon Kohden three items ECG, paper speed 50mm / s), each measuring not less than 9 lead, and full-time staff blinded by the manual measurement. QT interval of T the end of the T wave down wave branch of the intersection of the baseline, if the T wave descending branch point of intersection with the baseline is not clear or T wave after wave u, places T wave descending b