Midodrine treatment with Premarin older women with stress urinary incontinence Comparative efficacy and safety study.doc

 PAGE \* MERGEFORMAT 9 Midodrine treatment with Premarin older women with stress urinary incontinence Comparative efficacy and safety study [Keywords:] older women with stress urinary incontinence; midodrine hydrochloride; Premarin Stress urinary incontinence (FSUI) refers to the sudden increase in abdominal pressure cause involuntary urine flow, not pressure from the bladder wall detrusor contraction Zhang beat of urine caused by a clinical performance. Its characteristics are not the normal state enuresis, and abdominal pressure suddenly increased automatically when the urine outflow. FSUI is a common problem in older women, has been reported (1) adult female urinary incontinence prevalence rate of 23% to 44% of women aged 65 or older than the prevalence of 50%. Thus, treatment of the disease more and more attention gynecologist. In recent years many methods for the treatment of women FSUI but the effects are mixed (2), for the more obvious physiological dysfunction in patients with the treatment of elderly women FSUI few clinical studies. This observation of midodrine hydrochloride and estrogen premarin in the treatment of older women FSUI the efficacy and safety comparison. 1 Materials and Methods 1.1 General data observed in January 2004 ~ January 2008 in our hospital outpatient and inpatient treatment of elderly women FSUI 76 cases of patients randomized, balanced approach is divided into two groups. Which midodrine group of 40 patients aged 60 to 69 (mean 60.06 + -7.47) years, Premarin group of 36 patients aged 60 to 80 (mean 61.17 + -8.05) years; a course of 4 w. patients were Ingelmarn Sundberg category , degree FSUI (2 .) between the two groups of age, no difference between urinary incontinence symptoms (Pgt; 0.05). then failed to adhere to treatment in 5 cases, out for the following reasons: fear of cancer in 1 case, in violation of the program or on its own 3 cases of drug addition and subtraction, because of other exit 1 case of diseas