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Mifepristone and misoprostol for missed abortion Efficacy of 490 Cases
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Mifepristone and misoprostol for missed abortion Efficacy of 490 Cases
[Abstract] Objective of Mifepristone for the clinical effect of missed abortion. Methods in our hospital from January 2006 to December 2009 patients treated in 490 cases of missed abortion as the observation group were non-oral administration of m mifepristone 50 mg, once every 12 h, a total of 2 days, 3 days of oral misoprostol 0.6 μg. taken from January 1997 to December 2000 were 490 cases of missed abortion, oral diethylstilbestrol 3 mg, 3 times a day , even for 3 days and 4 days based on uterine size, 12 weeks pregnant line clamp curettage, 12 + weeks pregnant intravenous oxytocin, wait until the natural discharge of the fetus and placenta underwent curettage, tissue properties were observed case of natural discharge, vaginal bleeding, and curettage. Results observation group abortion rate was 92%; control group abortion rate was 40% in the observation group was significantly higher success rate of abortion. Conclusions Mifepristone with Misoprostol in the forefront alcohol can be safe and effective oral termination of missed abortion is effective and reduces the amount of post-abortion uterine bleeding, reducing the risk of incomplete abortion patients to avoid the occurrence of abortion syndrome, and there is medication method is simple, the advantages of small dosage.
[Keywords:] mifepristone; misoprostol; missed abortion
Missed abortion refers to the embryo or fetus is dead, stranded natural intrauterine not excreted [1]. Missed abortion is a special type of abortion, in the diagnosis, treatment and complications are at the same time so different from other types of abortion. missed abortion because of the timing of placental organization, in close adhesion with the uterine wall, past the treatment of multi-clamp with curettage or curettage, big pain in patients with this method, when the operation of technical difficulty and higher complication rate.
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