Minimal change nephrotic syndrome clinical and pathological features of acute renal failure.doc

 PAGE \* MERGEFORMAT 14 Minimal change nephrotic syndrome clinical and pathological features of acute renal failure [Abstract] Objective: To investigate the minimal change nephrotic syndrome (minimal change nephrotic syndrome, MCNS) with acute renal failure complicated by idiopathic (idiopathic acute renal failure, IARF) clinical and pathological features. Methods: A retrospective analysis of 15 adult MCNS concurrent IARF (renal failure group and outcome of clinical pathological conditions, randomly selected adult MCNS 15 cases of acute renal failure-free (non-renal failure group as the control. Results: The serum creatinine to renal failure group (307.7 +-168.6mol / L, oliguria type accounted for 73.3% (11 cases, acute renal failure improvement was 86.7% (13 cases). Compared with non-renal failure, renal failure severe edema group, systolic blood pressure levels higher (P lt;0.01), renal failure cloudy swelling group of tubular epithelial cells and tubular epithelial cells in a higher incidence of flattening (P lt;0.01, tubular cavity of the incidence of protein casts higher (P lt;0.05), nephrotic syndrome remission time and average hospital stay longer (P lt;0.01. Conclusions: Adult patients with primary clinical MCNS complicated IARF severe edema and high systolic blood pressure levels, pathological manifestations were acute tubular damage, mostly reversible renal function impairment, the prognosis is good . [Keywords:] nephrotic syndrome minimal change nephropathy with acute renal failure Abstract: Objective: To explore the clinical and pathological characteristics of minimal change nephrotic syndrome (MCNS complicated with idiopathic acute renal failure (IARF. Methods: Fifteen patients with adult-onset MCNS complicated with IARF (ARF group were compared with 15 patients with MCNS without ARF (non-ARF group who were randomly selected. The clinical manifestation, pathological data and outcome were analyzed retrospectively. Results: In ARF group the