Months of age and body weight in rats with acute myocardial infarction the incidence of ventricular fibrillation.docVIP

 PAGE \* MERGEFORMAT 12 Months of age and body weight in rats with acute myocardial infarction the incidence of ventricular fibrillation Of: Linchu Wei Zhang Chaixiang Ping Zhou Shenghua Li Yao Group [Abstract] Objective months and body weight in rats with acute myocardial infarction the incidence of ventricular fibrillation. Methods 2 months of age, 180 ~ 250 g SD rats (young group), and 15 months, 400 ~ 500 g SD rats (old group) to study 20; by thoracotomy look ligating ligation of left anterior descending coronary artery caused acute myocardial infarction, surgery center before and after surgical procedures and record the ECG electrocardiogram monitoring activities, Analysis of ventricular fibrillation were compared between groups such as the incidence of arrhythmia. results in acute ischemic myocardial infarction in the SD rat model, old age group the incidence of arrhythmia and ventricular fibrillation was significantly higher than the adult group (the incidence of arrhythmia: 85% vs 25 %, P lt;0.01; ventricular fibrillation incidence 55% vs 10%, P lt;0.01). Conclusions month high body weight in aged rats after acute myocardial ischemia induced ventricular fibrillation was significantly higher than the low month-old low birth weight in adult rats. [Keywords:] Acute myocardial infarction; the incidence of ventricular fibrillation; rat model [Abstract] Objective To explore the impact of months of age and body weight of rats on the incidence of ventricular fibrillation (vF) in acute myocardial infarction (AMI). Methods 2 month old, 180 ~ 250 g SD rats (youth group), and 15 month old, 400 ~ 500 g SD rats (old group) were selected; AMI rats models were made by open chest look directly method and the rats’ left coronary anterior descending artery were ligated. ECG was used to monitor and record cardiac electrical activity before and after surgical procedures. The incidences of vF and other arrhythmias were analyzed.Results In acute ischemic myocardia