Modified Fangjihuangqi on diabetic skin ulcers serum NO ET1 levels.doc

 PAGE \* MERGEFORMAT 10 Modified Fangjihuangqi on diabetic skin ulcers serum NO ET1 levels Of: yellow in the appointment of Markov Song Guangming Jin Yi Chai [Abstract] [Objective] Modified Fangjihuangqi on diabetic skin ulcers of vascular endothelial function. [Method] 90 SD male rats were randomly selected as control group 6, the rest of the tail vein of rats injection of alloxan 40mg/kg, select meet diagnostic criteria for diabetes in the rat model of diabetic skin ulcers for the establishment of modeling, and randomly divided into 6 groups, model control group, the Intervention Modified Fangjihuangqi high, medium and low dose group , medicine control group, comparison group. experiment were decapitated after blood test NO, ET 1 content to add and subtract Fangjihuangqi Tang on observation of the vascular endothelial function. [Results] Compared with model group, the treated group Serum NO levels were increased to varying degrees, while the levels of plasma ET 1 has a different degree of reduction, in which addition and subtraction soup Fangjihuangqi the most significant change in the high dose group (P lt;0.001), the dose was significantly (P lt;0.01), low dose, followed by medicine control group (P lt;0.05). Modified Fangjihuangqi soup regulation of each dose group significantly correlated with the dose. [Conclusion] Modified Fangjihuangqi soup by increased serum NO levels, decreased plasma ET 1 levels to improve endothelial function. [Keywords:] diabetes mellitus; skin ulcers; nitric oxide; endothelin-1; control; Fangjihuangqi soup Abstract: [Objective] To explore the cure effect of Astragalus Tetrandrae Decoction on vessel endodermis function of rats with diabetic derma ulcer. [Method] Select 90 SD male rats, take 6 as normal control group, others were injected by tail vein with Alloxan; choose rats in accordance with diabetic diagnosis to set up model of diabetic derma ulcer, and randomly divide them into 6 groups: model control (1), high, m