Morphological abnormalities induced by platelet apheresis platelets Failure Analysis.doc

 PAGE \* MERGEFORMAT 8 Morphological abnormalities induced by platelet apheresis platelets Failure Analysis [Abstract] Objective: To evaluate the output of the low platelet apheresis causes and preventive measures. Methods: The platelet product yield using Kurt AcT10 automatic instrument for blood cell count platelet count. Results: 4 bags of platelet product yield were lower than the ‘country of whole blood and blood components quality requirements’, analyze their causes. Conclusion: The four cases of the main reasons for the low platelet production in platelet morphology were caused by abnormal blood cell separator to collect and reducing efficiency. In the peripheral blood before apheresis blood donors routine screening should be a comprehensive analysis of the MPV, PDW and platelet histogram, in order to understand its platelet morphology, platelet better ensure the quality of the product. [Keywords:] platelet morphology; blood cell separator; collection efficiency As the transfusion of blood components to promote the application of the application of the proportion of platelets increased gradually, but repeated blood transfusion or platelets of patients, easy to produce platelet-associated antibodies, leading to platelet transfusion (platelet transfusion refraetoriness, PTR). PTR The primary reason is that the quality of platelet products [1], while the platelet morphology abnormalities that can affect platelet apheresis collection efficiency, so that product quality reach ‘whole blood and blood components state quality requirements’, thus affecting the clinical transfusion effect, and to increase the financial burden on patients. I stood on October 5, 2006, 6 and November 6 consecutive use of Trima Accel automated blood cell separator machine collected four cases of low platelet production. The author of its analysis of the causes, the report is as follows. 1 Data and methods 1.1 The clinical data of October 5, 2006, 6 and November 6 apheresi