Multifocal ERG in the early diagnosis of glaucoma.doc

 PAGE \* MERGEFORMAT 14 Multifocal ERG in the early diagnosis of glaucoma [Abstract] multifocal ERG (multifocalelectroretinogram, mfERG) in the ophthalmology field of application is the visual electrophysiology is an important new progress, using it to evaluate the outer and middle retinal dysfunction (such as the retina malnutrition) has been duly recognized the value of . However, with the multifocal ERG testing within the layer of retinal damage primarily based glaucoma, especially for early diagnosis, there are still many problems to be resolved. This article describes the multifocal ERG in the basic principles of normal multifocal ERG characteristics of glaucoma and ocular hypertension multifocal ERG changes and multifocal ERG and glaucomatous visual field defect relationship. [Keywords:] multifocal ERG; glaucoma; early diagnosis of Glaucoma is a common disease in China, accounting for blinding eye disease of the fourth population the incidence rate of about 0.21% ~ 1.64% [1], the number of glaucoma blindness accounted for 5.3% of the total number of blind people and 21% [2]. Therefore, early diagnosis of glaucoma is very important. In recent years, studies suggest that glaucoma inner retina (inner plexiform layer and ganglion cell layer) first appeared in the damage, so the inner retinal damage in early glaucoma detection is very important. The most commonly used method is vision testing, but studies have shown that conventional perimetry in glaucoma, abnormal, about 25% ~ 40% of the retinal ganglion cells have died [3], and irreversible change. Therefore, the search for visual function other than vision inspection methods and to refine or develop these methods, early diagnosis of glaucoma research is needed in efforts to explore direction. The 20th century, the early 90s, Sutter et al [4] proposed application of the multifocal ERG for quantitative evaluation of retinal function in clinical and scientific research has gradually get a promotion.