Multilayer amniotic membrane transplantation for necrotizing stromal herpes simplex corneal ulcer.doc

 PAGE \* MERGEFORMAT 14 Multilayer amniotic membrane transplantation for necrotizing stromal herpes simplex corneal ulcer [Abstract] Objective: To observe the multilayer amniotic membrane transplantation combined with antiviral drugs and corticosteroids necrotizing stromal herpes simplex corneal ulcer patients. Methods: The hospital inpatient 2002 10/2009 10 of 18 patients diagnosed with the disease cases of 18 eyes, the local and systemic anti-viral treatment 1wk or more, delayed healing of corneal ulcers, even expand, deepen the trend line of multilayer amniotic membrane transplantation to cover the surgery, after the United antiviral drugs and corticosteroids. Results : 18 patients after healing of corneal ulcers, including restoration of corneal transparency in 8 patients, 10 patients formed the limitations of corneal nebula, or white spots. 1 case of ulcer patients after amniotic membrane transplantation, the ulcer healing, but the formation of scar poor eyesight, 1a to the line after corneal transplantation. Conclusion: fresh multilayer amniotic membrane transplantation combined with antiviral drugs and corticosteroids to treat necrotizing stromal herpes simplex keratitis is a simple, economical and effective treatment for increasing visibility, allow patients to return part of the vision or maintain the integrity of the cornea for corneal transplantation for the opportunity. [Keywords:] amniotic membrane transplantation, necrotizing stromal keratitis Abstract AIM: To evaluate the efficacy of multilayer amniotic membrane transplantation combined with antivirus and glucocorticosteroid drug to treat necrotizing herpes simplex stromal keratitis. METHODS: Eighteen patients (18 eyes) of necrotizing herpes simplex stromal keratitis were referred to the central hospital of Enshi Autonomous Prefecture between October 2002 and October 2009. Corneal inflammation persisted and corneal ulcer progressed despite topical and systemic antiviral treatment for o