Neonatal hypoxic ischemic encephalopathy treatment and care.doc

 PAGE \* MERGEFORMAT 9 Neonatal hypoxic ischemic encephalopathy treatment and care Of: WANG Yan Zhimin Peng Gao Yan Qin [Keywords:] hypoxic ischemic encephalopathy, cerebral edema, mannitol, Albumin in cerebral edema is a hypoxic-ischemic encephalopathy (hypoxic ischemic encephalopathy, HIE) in children with primary brain pathophysiological changes. The traditional use of mannitol dehydration treatment methods to correct brain edema, our department with the first dose of mannitol plus subsequent infusion of albumin method for treating neonatal HIE 18 cases, good results. 1 Materials and Methods Our department in October 2003 ~ August 2005 112 patients were treated newborns, 39 cases selected by a clear history of choking and head CT examination of clinical diagnosis of HIE, neonatal cerebral edema were randomly divided into two groups. Observer Group 18 cases, including 4 cases of premature children, 14 cases of term labor, cesarean section in 6 cases, 12 cases of natural childbirth. the control group 21 cases, 8 cases of premature children, full term in 13 cases, 12 cases of cesarean section and natural childbirth 9 cases. the two groups no significant difference in birth weight (Pgt; 0.05). All the children were given neonatal HIE, brain edema, and support of conventional treatment. mannitol dosage for each of the control group, 0.5 ~ 0.75 g / kg body weight, according to severity of symptoms 3 to 4 times / d, intravenous injection, as adjusted for changes in the amount and frequency of illness, of which 3 cases (1 case of premature children, full-term children in 2 cases) the use of mannitol 36 ~ 54 h after the due oliguria, creatinine Jicha , urea nitrogen, were higher, considering the suspension of acute renal failure with mannitol, and the remaining 17 patients with 72 ~ 96 h mannitol disabled. observation group to give the first dose of mannitol 0.75 g / kg body weight, intravenous injection, 30 min after given to human serum albumin 2 ~ 4