Neurological complications after liver transplantation Research Progress.doc

 PAGE \* MERGEFORMAT 10 Neurological complications after liver transplantation Research Progress Liver transplant surgery is an important means of end-stage liver disease in recent years, in the patient selection, surgical techniques, immunosuppressive treatment programs, there has been significant progress. However, complications continue to occur, the nervous system post-transplant complication rate as high as 13% to 47% [1], is the cause of death in patients after liver transplantation in one of the main. Its various clinical manifestations include severe encephalopathy, partial nervous system abnormalities, seizures, and neuromuscular disorders. 1. Encephalopathy encephalopathy after liver transplantation in the most common neurological complications after liver transplantation has been reported, more than 80% of receiving a liver transplant patients after surgery there are different degrees of encephalopathy [2]. These symptoms are typical, but not unique, of which about 70% occurred within 2 weeks after surgery, usually lasting a few days time, some of onset more than 1 weeks or more [3,4]. 1.1 after liver transplantation in patients with diagnostic criteria for encephalopathy after liver transplantation compared with the preoperative data, such as marked headache, dysarthria, cerebellar ataxia, psychiatric symptoms (such as emotional instability, anxiety, depression, delirium, and the trance state of mind paranoia, etc.), extrapyramidal symptoms (such as tremor, etc.), severe cases, hallucinations, convulsions and even coma, after a doctor of neurology consultation and to exclude epilepsy, cerebrovascular disease, intracranial infections, peripheral neuropathy, and extrapyramidal diseases, were diagnosed with encephalopathy after liver transplantation. If surgery is associated with hepatic encephalopathy before and after neuropsychiatric symptoms have not improved significantly compared with the preoperative liver transplant recipients who are not cove