No intravenous fluids in dogs under hemorrhagic shock on the circulation of early oral rehydration index of oxygen dynamics.doc

 PAGE \* MERGEFORMAT 16 No intravenous fluids in dogs under hemorrhagic shock on the circulation of early oral rehydration index of oxygen dynamics Of: Husen, Li Lin, Hou Jing Yuan, Wang Ruichen [Abstract] Objective To study the blood volume in dogs after blood loss 40% of the cycle of early oral rehydration index of oxygen dynamics. Methods 20 Beagle dogs, the initial sterile surgical carotid artery and vein catheterization, 24 hours after the blood volume by body 40% of the bleeding hemorrhagic shock model. randomly divided into groups without rehydration (n = 8), oral rehydration group (n = 6) and intravenous fluid infusion group (n = 6). blood loss after a 24-hour infusion group did not No treatment, oral rehydration and intravenous fluid replacement group respectively input from the stomach or 3 times the blood loss, intravenous glucose electrolyte solution. 24 hours after blood loss from the 3 groups were given intravenous fluids. Determination of non-anesthetized animals, mean arterial pressure (MAP ) and hematocrit (HCT), arterial and mixed venous blood collected measured arterial and venous partial pressure of oxygen and blood oxygen content (CvO2), calculate the amount of oxygen supply (DO2) and oxygen consumption (VO2), and 3 days of death statistics number. Results hemorrhage group 3 dogs MAP, PaO2, DO2 and VO2 were significantly lower, PaCO2 increased significantly. two fluid group, these indicators of rapid recovery, blood loss 72 hours after the PaO2, PaCO2 and pH were restored to the loss of blood before (0 hours) level, but the DO2 and VO2 remained below the level of 0 hours. oral rehydration group of MAP, PaO2 and pH recovery was better than no fluid resuscitation group, but worse than intravenous fluid group; PaCO2 changes in contrast. DO2 blood loss, oral rehydration group 4 , 8,24-hour infusion group was significantly higher than, but less than 24 hours after the intravenous infusion group (P lt;0.05); VO2 within 4 hours after blood l