Of nitric oxide with human embryonic cerebellar development of relations between the research.doc

 PAGE \* MERGEFORMAT 10 Of nitric oxide with human embryonic cerebellar development of relations between the research 【Abstract】 NO as the chemical sector, “star elements”, with its unique biological nature of the organism involved in various physiological functions and diseases of the formation process, and more and more attention. In this paper, conclusions of previous studies focusing on the NO in the human embryonic brain development and its role in the distribution of research results were reviewed. Keywords: nitric oxide; nitric oxide synthase; human fetal brain 【Abstract】 Nitric oxide (NO) known as “the star member” in the chemistry circles has drawn more and more attention. It participats in many physiological functions and disease formation by it’s special biology nature. This article overviews the distribution and function of NO during the human fetal brain development, combining with the previous research. 【Keywords:】 nitric oxide; nitric oxide synthase; human fetal brain In 1980, Furchgott and so in the vascular endothelial cells found in endothelium-derived relaxing factor (endothelium derired relaxing factor, EDRF), can stimulate the vascular smooth muscle relaxation, but also mediated a number of endogenous and (or) exogenous substances Shu vascular response; 1987 Palmer et al study has confirmed the EDRF is nitric oxide (nitric oxide, NO), is an information molecule with biological activity. In 1991, a nitric oxide synthase (nitric oxide synthase, NOS) successful cloning. In 1992, Science magazine named NO molecules year “star elements.” With NO present the progress of basic research and found that the biological role of NO involves many disciplines and to participate in a variety of body physiology and disease formation process, has become the hot domestic and international medical research in the field, and one front. 1 NO biological nature of the biological activity of NO is a relatively small mo