On Pneumocystis carinii pneumonia in the treatment of disease.docVIP

 PAGE \* MERGEFORMAT 8 On Pneumocystis carinii pneumonia in the treatment of disease [Abstract] Objective To improve Pneumocystis carinii pneumonia (PCP) knowledge and treatment. Methods Retrospective analysis of 9 patients with clinical manifestations, laboratory tests, imaging studies, bronchoscopy data. Conclusion Pneumocystis carinii pneumonia Acute respiratory failure associated with poor outcome, strive for early diagnosis and treatment is to improve the survival rate of the key. [Keywords: Pneumocystis carinii pneumonia Pneumocystis carinii disease, also known as the card’s alveolar carinii pneumonia, is the card caused by Pneumocystis carinii pneumonia interstitial plasma cell, is the condition of pulmonary infections. The disease of the 20th century only 50 years ago found in preterm children, infant malnutrition, nearly 10 years with the immunosuppressive agents to the application of the popularity of cancer chemotherapy, in particular the emergence of AIDS disease, the incidence rate was significantly increased in patients with AIDS has become the most common opportunistic infection and death of the main causes. The vast majority of violations of lung disease, Cryptosporidium parasite adhesion in alveolar epithelial cells. Alveolar epithelial hyperplasia, interstitial lung infiltration of inflammatory cells to plasma cells, mainly lymphocytes, and with exudation, edema, fibrosis. Cause pathophysiological aspects of change is hypoxemia, decreased lung compliance and vital capacity, total lung capacity decreased. 1 Clinical data 1.1 General information on our hospital from August 2004 ~ December 2009 diagnosis of 9 cases of Pneumocystis carinii pneumonia in patients, including 5 males and 4 females, aged from 12 to 68 years, mean age 40 years. Through clinical manifestations , laboratory tests, imaging studies, bronchoscopy lavage detected in 22.2%, bronchoscopy lung biopsy detected 55.6%, PCR method confirmed in 2 cas