On the grass before the soup on the three chronic non-bacterial prostatitis rat model of IL-1β IL-6 and TNF R Ⅱ expression.docVIP

 PAGE \* MERGEFORMAT 15 On the grass before the soup on the three chronic non-bacterial prostatitis rat model of IL-1β IL-6 and TNF R Ⅱ expression Of: Zhou Qing, Xiong, Zhang Guomin, radius, Xiaohong Yu, Gong Xiuying [Abstract] Objective To observe the three grass soup of security before the chronic non-bacterial prostatitis rat model of inflammatory cytokine interleukin-1β (IL-1β), interleukin -6 (IL-6) and tumor necrosis factor receptor Ⅱ (TNF R Ⅱ) gene and protein expression, to clarify traditional Chinese medicine treatment of chronic non-bacterial prostatitis inflammatory protein targets. Methods 72 healthy male Wistar rats were randomized into 6 groups, 12 in each group, in addition to the normal group, the other five group applications supported by rat prostate protein purified liquid preparation of experimental chronic immune adjuvant non-bacterial prostatitis rat model, the normal group, model group to the saline group were given anti-inflammatory pain medicine, three grass before security soup large, medium, low dose group were given three different doses of grass soup before security were killed after intragastrically .30 d, by immunohistochemistry, quantitative RT-PCR were used to detect mRNA and protein expression of inflammatory factors. Results The Grass On the former soup can significantly reduce the chronic non-bacterial prostatitis rat model of inflammatory cytokines IL-1β, IL-6 mRNA and protein expression of (P lt;0.01), and the large, medium dose group was superior to low dose group (P lt;0.05), large, medium dose group compared with the normal group was no significant difference (Pgt; 0.05), three grass soup before security TNF R Ⅱ each dose group was decreased, no significant change with dose (Pgt; 0.05). Conclusion On the three grass before the Tang on chronic non-bacterial prostatitis rat model of abnormal regulation of immune function, reducing the expression of inflammatory factors in the treatment of chronic prostatitis is an im