Outpatient antibiotic prescribing common problems and countermeasures.docVIP

 PAGE \* MERGEFORMAT 8 Outpatient antibiotic prescribing common problems and countermeasures [Keywords:] antibiotics, prescription audit, evaluation, Strategy broader clinical application of antibiotics is one of the drugs, the drug resistance has become a global concern. Drug resistance and abuse of antibiotics, the correct use of antibiotics is a reasonable increase efficacy and reduce the incidence of adverse reactions and bacterial resistance to reduce or mitigate The key herbs occurred. our hospital outpatient antibiotic prescriptions perform the audit, reviews, evaluation system and found that there are some common problems. An analysis of outpatient antibiotic prescriptions FAQ 1.1 inappropriate dosing regimens largely inappropriate to penicillins, cephalosporins typical of most of the atypical -lactams and clindamycin and other time-dependent antibiotics, intravenous administration of 1 / d , mostly concentrated in 2 ~ 4 h run out, during the administration of a high blood concentration, most of the remaining difficult to maintain effective plasma concentrations. this administration method is not only antibacterial effect can not be achieved, but easy to induce resistant bacteria property. mainly due to intravenous administration several times a day inconvenient, it is difficult to accept patients, and patients with mild, mostly outpatient. Such rational dosage regimen of antibiotics is to shorten the time interval, without having to increase the dose each time the general half-life of 3 to 4 dosage 1 day to 3 to 4 minutes total drug dose [1]. However, this drug delivery door in terms of its emergency patients with poor compliance. recommended first intravenous drip Note 1 drug, and then changed to oral dosage forms using the same dose of drugs, this method is more suitable for ambulatory patients [2]. 1.2 Improper use of the most typical solvent is soluble in 5% of penicillin or 5% glucose intravenous infusion of glucose and sodium chlor