Overview of transfusion of platelets is not valid.docVIP

 PAGE \* MERGEFORMAT 15 Overview of transfusion of platelets is not valid [Abstract] invalid platelet transfusion (PTR is a problem of clinical blood transfusion, which occurs with non-immune factors and immune factors are closely related. Immunological factors are HLA, HPA, ABH and other antibodies, non-immune factors are infection, fever, spleen nodes, bone marrow transplantation, DIC and so on. In this paper, the criteria for determining recent PTR, influencing factors, prevention and treatment were reviewed. [Keywords:] is not valid platelet transfusion non-immune factors in the immune factors The main function of platelets is involved in physiological hemostasis and promote blood clot contraction and maintain the integrity of vascular endothelium in the blood coagulation plays an important role. Hematology and oncology patients in the treatment or progression of disease, and more associated with thrombocytopenia, platelet transfusion is the main treatment, has important clinical value. but have a variety of factors may lead to ineffective platelet transfusion, thus affecting the clinical efficacy of platelet transfusion. Therefore, platelet transfusions are not valid clinical transfusion medicine needed to solve a problem . This paper discusses the relevant literature. 1 platelet transfusion is not valid Invalid platelet transfusion (platelet transfusion refractoriness, PTR that enter the body in patients with a rapid destruction of platelets, peripheral blood platelet count failed to increase correspondingly, thus unable to control due to the insufficient number of platelets or platelet dysfunction caused by hemorrhagic bleeding [1] . repeated platelet transfusions in patients, PTR was 30% to 70% [2]. 2 PTR criteria The diagnosis is currently no uniform standard PTR, most scholars believe that [1] can be used to increase platelet correction index (CCI and platelet recovery (PPR to evaluate. CCI is based on patient body surface are