Oxaliplatin leucovorin and fluorouracil in the treatment of advanced gastric cancer clinical observation of 28 cases of.docVIP

 PAGE \* MERGEFORMAT 6 Oxaliplatin leucovorin and fluorouracil in the treatment of advanced gastric cancer clinical observation of 28 cases of [Keywords:] Austria platinum; CF; 5 Abstract: 28 cases of advanced gastric cancer patients to take Austria-platinum, tetrahydrofolate (CF), 5Fu combination chemotherapy, with a total effective rate 464%, complete remission rate of 36% of patients showing good tolerance, have some clinical value . Keywords: Austrian platinum; CF; 5Fu combination therapy; With advanced gastric cancer Gastric cancer is one of common malignant tumors in China, the mortality rate ranks No. 2 cancer [1], the loss of surgical timing and recurrence after surgical treatment for patients with advanced gastric cancer with chemotherapy can improve the quality of life and prolong survival. In this study, oxaliplatin (Eloxatin), CF, and 5Fu treatment of 28 patients with advanced gastric cancer patients was observed efficacy and adverse reactions. A clinical data 11 General Information In our hospital from October 2002 ~ October 2005 admitted 28 patients with advanced gastric cancer, pathological diagnosis is no longer operative, post-operative recurrence or metastasis of gastric cancer patients, 28 cases had measurable lesions. KPS score ≥ 60 points, are expected survival time in 3 months. Of which 20 males and 8 females. Aged 20 to 70 years, with an average 605-year-old. Pathological types: poorly differentiated adenocarcinoma in 10 cases, 6 cases of mucinous adenocarcinoma, signet-ring cell carcinoma in 2 cases, moderately differentiated adenocarcinoma in 10 cases. Routine blood test, liver, kidney function, electrolytes, blood sugar, ECG were normal, untreated in 18 cases, re-treatment in 10 cases. 12 treatment Oxaliplatin 60mg/m2 adding 50ml of 5% glucose intravenous infusion 2 hours, d1, d8, CF150mg/m2 normal saline intravenous infusion 2 hours d1 ~ 5,5 Fu 500mg/m2 by adding normal saline intravenous drip 4 hours d1 ~ 5, of the above op