P300 event-related potentials and cognition research.docVIP

 PAGE \* MERGEFORMAT 9 P300 event-related potentials and cognition research Study: Pan-speed Europe Xiaofan Huang Yue Ying Ji Xinbo [Keywords:] event-related potentials P300, cognitive function, neuropsychology Neuropsychological test is a brain disorder diagnosis and assessment of mental activities, the tools to quantify, can reflect the person’s cognitive function. In recent years, event-related potential P300 cognitive function as a more objective reflection of the biological indicators, in recognition the study of cognitive function are more and more attention (1,2). This paper aims to clarify the use of neuropsychological test results of the cognitive significance of P300, which will in future clinical evaluation of cognitive function in a more comprehensive, objective indicators. 1 Subjects and methods 1.1 study A total of 120 subjects, are in hospital health examination center examination of healthy volunteers. Inclusion criteria: right-handed, volunteered for this study, no neurological, mental illness or severe physical illness, no family history of mental illness, non- color blindness, color weak. subjects male and female 60; subjects aged 20 to 66 (mean (48 + -16)) years old, 11 to 18 years of education (mean (14.2 + -1.8)) years. 1.2 Methods P300 detection methods: The subjects were asked to check for P300, the experimental apparatus, Beijing Newcomen’s MEDICID 3E with cerebral evoked potential. Recording electrodes by the standard 10/20 International EEG Society placed FZ, CZ, PZ, OZ, C3, C4, T3, T4 points, the two mastoid as a reference electrode (A12), FPz ground impedance between the electrode and the skin is less than 5 k. use visual images to identify operating at the “target / non-target” sequence evoked by stimulation try’s P300, the target and the probability of non-target stimuli than for the 0.2/0.8, the total boost of 250 times, each stimulus presentation lasted about 500 ms, the two stimulus interval 500 ms. tra