Patients with lung cancer study of serum lipid peroxidation.doc

 PAGE \* MERGEFORMAT 7 Patients with lung cancer study of serum lipid peroxidation Of: Yan Qiao Mei Zhen Wang Dengkui Chengxiang Hui Miao change Wei Pang East [Abstract] Objective: To investigate the lung cancer patients with serum lipid peroxidation level. Methods: The patients with lung superoxide dismutase (SOD, malondialdehyde (MDA), nitric oxide (NO) and sialic acid (SA) content to evaluate patients with lung cancer the extent of lipid peroxidation. Results: Compared with normal human serum, lung SOD activity was significantly lower in patients (P lt;0.01, MDA was significantly higher (P lt;0.01, SA was significantly higher (P lt;0.01, SOD / MDA was significantly lower (P lt;0.01. Conclusion: The serum lipid peroxidation in patients with lung cancer increased. [Keywords:] lung cancer, lipid peroxidation, superoxide dismutase, malondialdehyde, nitric oxide, sialic acid Lung cancer is one of common malignant tumors in recent years, morbidity and mortality is rising, its pathogenesis has not yet fully understood, many studies suggest that the incidence of this disease associated with smoking, atmospheric and air pollution, viruses and so on. by many environmental factors that stimulate free radical reactions in vivo, can exacerbate cell unsaturated fatty acids lead to membrane lipid peroxidation injury, which may be mediated by toxic and even carcinogenic damage caused by the pathological basis of [1]. In order to investigate lung cancer serum lipid peroxidation levels in 40 patients with lung cancer serum lipid peroxidation were studied, aimed at further understanding of lung cancer, the development process, to provide some clinical testing and the prevention of theoretical and experimental basis. 1 Materials and methods 1.1 Materials normal serum: the crowd from the normal physical examination, a total of 30 people, including 16 males and 14 females, age range 23 to 58 years, the average age of 40.7 years. Lung cancer patients: from the Fi