Peach Decoction mice Lewis lung cancer study.doc

 PAGE \* MERGEFORMAT 12 Peach Decoction mice Lewis lung cancer study Author: Cao Zhiyou Wang Shuang Ouyang Jin-Tao, Wang Xin-Cheng Leijun [Abstract] Objective To investigate the peach decoction of the Lewis lung cancer model mice the therapeutic effect and its mechanism. Method to copy C57BL / 6 mice with Lewis lung cancer model, 40 mice were randomly divided into four groups: the saline group (A group), white peach soups with low-dose group (B group), white peach decoction of high-dose group (C group), cisplatin (DDP) group (D group), continuous medication 10 d, observed the growth of tumor transplants, using radioimmunoassay of serum tumor necrosis factor-α (TNF-α ), interleukin -6 ( IL-6) levels. Results A group of tumor mass of the most weight, with the other group differences were statistically significant (P amp;lt;0.01). D, C group may be elevated serum TNF-α level (with the A group, P amp;lt;0.01 or P amp;lt;0.05), B, C group can significantly reduce the IL-6 levels (with the A group, P amp;lt;0.01). Conclusion peach decoction could increase anti-tumor effect may be related to the level of serum TNF-α and lower IL-6 levels, improve immune function. [Keywords:] peach decoction of lung cancer disease model mice At present, lung cancer ranks of China’s urban population, the incidence of the first, has become the highest cancer incidence and mortality of cancer diseases, to date no effective treatment. At present the medical profession generally agreed that measures to improve the efficacy of lung cancer is a multidisciplinary and comprehensive treatment, in which Chinese medicine treatment occupies an important position. Peach decoction for civil secret prescription, many patients who have lifted off illness, the clinical cure rate of 76%. In this study, treatment of Lewis lung cancer observed in mice peach soups efficacy and mechanism is designed to further the drug in clinical applications provide a scientific basis. 1 Materials and equipment