Patients with acute cerebral infarction IL-6 levels and WBC counts in peripheral blood of.docVIP
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Patients with acute cerebral infarction IL-6 levels and WBC counts in peripheral blood of
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Patients with acute cerebral infarction IL-6 levels and WBC counts in peripheral blood of
[Abstract] Objective: To study patients with acute cerebral infarction IL-6 levels and peripheral blood WBC count and the dynamic changes of the correlation between the two. Methods: The double antibody sandwich ELISA method in 30 patients with acute cerebral infarction, respectively, after stroke 1 day, 3 days, 7 days, 14 days of continuous detection of serum IL-6 and the peripheral blood WBC count, and 30 healthy persons. Results: Compared with normal control group, in the course of 1 day, 3 days, 7 day 3 time points of serum IL-6 levels and peripheral blood WBC counts were significantly higher (P lt;0.05), serum IL-6 in the course of the disease was significantly higher on day 1 and reached a peak (P lt;0.05, the duration of peripheral blood WBC count increased significantly at day 3 and reached a peak (P lt;0.05), both with the infarct size, neurological impairment was positively correlated (P lt;0.05), and significant correlation between the two (r = 0.4, P lt; 0.05. CONCLUSION: Cerebral infarction associated with inflammation, and inflammatory response in ischemic brain injury, WBC, IL-6 in this process play an important role, and a positive correlation between the two. IL-6 is mediated by inflammatory cytokine response , play the role of immune regulation. How block the inflammatory reaction of cerebral protection will be the new effective way of treatment.
[Keywords:] cerebral infarction, IL-6, IL
Abstract Objective: To investigate the changes in the serum levels of IL-6 and the number of leukocytes in peripheral blood of the patients with acute cerebral infarction and their correlation to each other. Methods: By using ELISA, we serially measured the serum levels of IL-6 and counted the number of leukocytes in peripheral blood of 30 patients with acute cerebral infarc-tion at day 1, day 2, day 7 and day 14.The measure was also taken
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