Pediatric clinical significance of penicillin sensitivity again.docVIP

 PAGE \* MERGEFORMAT 4 Pediatric clinical significance of penicillin sensitivity again [Abstract] Comparison of the clinical application of penicillin is a wide range of antibiotics, there are high efficiency, low toxicity, low cost, etc., but its side effects are allergic reaction, must be used before the skin test to determine whether the use of skin test results to determine standards to bring some of the difficulties of clinical treatment, the clinical application of it so cautious, but also need to make the process of penicillin skin test must be careful in making judgments. [Keywords:] penicillin; skin test; judge the outcome Penicillin antibiotics as high efficiency, low toxicity, low cost, etc., is the treatment of bacterial infections of the drug, it is widely used in clinic. But are allergic to penicillin side effects, general health clinics and private clinics and medical rescue equipment by the limited conditions, and to avoid the occurrence of allergic reactions to penicillin, any relaxation of the penicillin skin test results to determine the standard, so many patients (especially younger children) for “positive” and can not use penicillin to clinical difficult. clinical trial as epithelial “positive” generally high, so that the application of the drug undue restrictions, has caused great inconvenience to patients. Since 2005-2009, we determine the penicillin skin test on the original “positive” patients children 60 cases were re-penicillin skin test, contralateral saline control trials simultaneously, the results reported below. 1 Clinical data 1.1 General information on 60 cases in children less than 4 years old, male or female, were originally judged to be penicillin skin test “positive” who had systemic symptoms excised. 1.2 The test methods on the original penicillin skin test “positive” patients in emergency preparedness and make full under close observation to do skin test, using isotonic saline preparation of penicillin s