Periodontal ligament cells implanted in the amount of volume and the relationship between periodontal tissue regeneration in animal experiments.doc

 PAGE \* MERGEFORMAT 16 Periodontal ligament cells implanted in the amount of volume and the relationship between periodontal tissue regeneration in animal experiments [Abstract] Objective number of different periodontal ligament cells (PDLC implanted in experimental chronic periodontal defects, the observed number of cells implanted with the relationship between the amount of periodontal tissue regeneration, can promote regeneration of periodontal tissues to determine the effective cell concentration and effective cells. Methods of constructed four Beagle dogs with experimental chronic periodontal defect model (5 mm 5 mm 3 mm U-alveolar bone defects), respectively, containing 1 104,1 105 and 1 106 PDLC implantation of collagen membranes in periodontal defects .12 weeks after the histological measurement of new cementum (NC) percentage and length of new bone (NB) area percentage of parallel statistical analysis. The results are visible in different groups degree of periodontal tissue regeneration, 1 104 PDLC group and 1 105 PDLC compared with the control group no significant difference, 1 106PDLC group NB area percentage was significantly higher than the control group. Conclusions The implantation of experimental periodontal defects into the PDLC, can promote periodontal tissue regeneration, the effective concentration of 5 107 mL-1, the effective number of 1 106 PDLC. [Keywords:] cells cultured periodontal ligament periodontal guided tissue regeneration in periodontal tissue engineering The ultimate goal of periodontal therapy is to prevent the further development of disease, and to achieve periodontal regeneration. In recent years the rapid development of periodontal tissue engineering of periodontal treatment is to open up a new way, the seed cells choose to become focus of attention of foreign scholars . periodontal ligament cells (periodontal ligament cells, PDLC as the advantages of periodontal tissue cells, is a group of more than the