Phlegm descending gas capsule on the treatment of chronic obstructive pulmonary disease the role of the inner mechanism of.doc

 PAGE \* MERGEFORMAT 15 Phlegm descending gas capsule on the treatment of chronic obstructive pulmonary disease the role of the inner mechanism of Authors: Li Ze-geng, Zhang Jie root, Peng Bo, Zhang Nian-Zhi, Han to the [Keywords:] phlegm descending gas capsule;,, chronic obstructive pulmonary disease;, and tumor necrosis factor-α ;,, leukotrienes;,, rat Abstract: Objective: To explore the phlegm descending gas capsule on experimental treatment of chronic obstructive pulmonary disease, the role of the internal mechanism. Methods: The nasal cavity into the Klebsiella pneumoniae replication repeated infection with chronic obstructive pulmonary disease model rats, experiments were divided into control group, model group and the phlegm descending gas capsule group. Using enzyme-linked assay (ELISA) method for the determination of the rats in bronchoalveolar lavage fluid tumor necrosis factor (TNFα ), leukotriene (LTB4) levels. Results: The model group, bronchoalveolar lavage fluid TNFα , LTB4 levels were significantly higher than the normal group (P amp;lt;0.01); phlegm descending gas capsule group bronchoalveolar lavage fluid TNFα , LTB4 were significantly lower (P amp;lt;0.05). Conclusion: The lower gas capsule can reduce phlegm TNFα , LTB4 levels, control of chronic inflammatory response. Keywords:: phlegm descending gas capsule; chronic obstructive pulmonary disease; tumor necrosis factor-α ; Leukotriene; rat Effect on the Level of TNFα , LTB4 in Bronchoalveolar Lavage Fluid of Model Rats with Chronic Obstructive Pulmonary Disease by Huatanjiangqi Capsule Abstract: Objective: To observe the effects of Huatanjiangqi Capsule, a combination of traditional Chinese medical herbs on the changes of TNFα , LTB4 in Bronchoalveolar Lavage Fluid, in order to provide basis for the explanation of the mechanisms of Huatanjiangqi Capsule and discover it’s pathophysiological characters . Methods: According to the principle of random, 36 Wistar rats (male) were divided in