Piperacillin-sulbactam combination therapy with a penicillin secondary syphilis evaluation of the efficacy and adverse reactions_0.doc

 PAGE \* MERGEFORMAT 12 Piperacillin-sulbactam combination therapy with a penicillin secondary syphilis evaluation of the efficacy and adverse reactions [Abstract] Objective To evaluate the piperacillin and sulbactam sodium combination therapy with a penicillin, the efficacy in patients with secondary syphilis and adverse reactions. Methods A retrospective analysis of our hospital in December 2008 ~ October 2009 72 patients admitted to a , The clinical data of patients with secondary syphilis, all patients were randomly divided into treatment group and control group 36 cases, the treatment group were piperacillin and sulbactam sodium combination therapy with penicillin, the control group treated only with penicillin, compared analysis of two groups of clinical efficacy and adverse reactions. Results The cure rate of treatment group, 83.3%, significantly higher than the 61.1% between the two groups was significant difference (P lt;0.05); the treatment of adverse reactions rate was 8.3%, 13.9% lower than the control group between the two groups no significant difference (Pgt; 0.05). Conclusion piperacillin and sulbactam sodium combination therapy with benzathine penicillin one to obtain more secondary syphilis good effect, and fewer adverse reactions, is worthy of clinical application. [Keywords:] syphilis; early; piperacillin and sulbactam sodium; penicillin; effect; adverse reactions Abstract Objective To evaluate the curative effect and side effect of the combined treatment with piperacillin sulbactam sodium and benzathine penicillin on primary and secondary syphilis.Methods A retrospective analysis was made to the clinical data of 72 cases with primary or secondary syphilis; they were randomly divided into 2 groups: treatment group and control group, 36 cases in each; the combined treatment with piperacillin sulbactam sodium and benzathine penicillin was given to patients in treatment group while only benzathine penicillin was given to patients in co